IGFBP7 and neoplasm: Our comprehensive omics analysis revealed IGFBP7-AS1 may improve the tumor immune microenvironment, and impact on immune lymphocytes like T cells, Mast cells, Macrophages M1 and M2, including key immune checkpoints with its target gene IGFBP7, so that help to induce protective immunity in UCEC and provide a new reference for potential UCEC immunotherapy.