KLF5 and nasopharyngeal carcinoma: The reporter with the wild-type KLF5 3'-UTR showed decreased luciferase activity in NPC-TW03 and NPC-TW04 cells following transfection with miR-145-5p mimics, and was reversed in the presence of mutated KLF5 3'-UTR in comparison to that of the scrambled control (Fig. 4e).