DNMT3A and cyclic hematopoiesis: Among cytokines, genetically elevated circulating macrophage inflammatory protein 1a, a regulator of myeloid differentiation and HSC numbers66, was associated with risk of DNMT3A-CH (OR = 1.13, 95% CI 1.03–1.23, P = 7.1 × 10−3; Supplementary Table 38).