HSP90AA1 and neoplasm: As shown in Fig. 3H, in comparison to LRP-1 down-regulation (panel n), neither Hsp90α-KO, α-KO-#1 cell, (panel o) nor anti-Hsp90α neutralizing antibody, mAb1G6-D7, (panel p) was able to achieve a complete inhibition of the self-supported motility of the tumour cells.