CLEC2D and infection: In contrast, adoptive transfer of wild-type MDSCs induced by GM-CSF plus GXM into Clec2d-deficient mice significantly increased their pulmonary fungi burden and Arg1 expression to suppress the function of IFN-γ-producing TH1 cells and IL-17A-producing TH17 cells after infection with C. neoformans encapsulated strain H99.