As shown in figure 2A, we did not observe a statistically significant difference in the autophagy marker protein, LC3BII, but we did observe a profound increase in the autophagy substrate protein, sequestosome 1 (SQSTM1/p62) in IPF fibroblasts as compared to those of HD. The gene discussed is SQSTM1; the disease is idiopathic interstitial pneumonia.