Univariate analysis showed that age (P = 0.024), BMI (P = 0.015), CEA (P < 0.001), CA19‐9 (P < 0.001), Borrmann type (P < 0.001), tumor diameter (P < 0.001), tumor location (P < 0.001), pTNM stage (P < 0.001), NPS (P < 0.001), PNI (P < 0.001), SIS (P = 0.014), venous invasion (P < 0.001), nerve infiltration (P < 0.001), lymph node metastasis rate (P < 0.001), vascular infiltration (P < 0.001), and postoperative chemotherapy (P = 0.002) were statistically significant. Here, CEACAM5 is linked to neoplasm.