Coagulopathy, characterized by elevated von Willebrand factor, fibrinogen, and D‐dimers and leading to excessive thrombin production, inhibition of fibrinolysis, and complement activation, has been associated with infection‐mediated endothelialitis and endothelial injury (Gupta et al, 2020; Varga et al, 2020). The gene discussed is VWF; the disease is infection.