CLIC1 and neoplasm: High CLIC1 expression has been reported in a range of malignant tumours (Gritti et al., 2014; Setti et al., 2015; Tian et al., 2014; Wang et al., 2011; Zhang et al., 2015; Zhao et al., 2015) and cardiovascular diseases such as pulmonary hypertension (Abdul-Salam et al., 2010) and ischaemic cardiomyopathy (Gronich et al., 2010).