The ATX inhibitor EX_31, a tetrahydrocarboline derivative with unclear binding mode, did not show any effect on liver‐related markers in a 10‐week CCl4‐induced liver fibrosis and 14‐week choline‐deficient amino acid‐defined diet (CDAA)‐induced NASH rat models (Baader et al, 2018). This evidence concerns the gene ENPP2 and metabolic dysfunction-associated steatohepatitis.