m6A/m5C/m1A regulated genes YBX1, ZC3H13, YTHDF1, TRMT10C, YTHDF2, RRP8, TRMT6, LRPPRC, and IGF2BP3 are the influencing factors of poor prognosis in HCC patients. The gene discussed is YTHDF2; the disease is hepatocellular carcinoma.