As illustrated in Figures 4A, B, the top 20 pathways of GO and KEGG were selected separately according to the absolute value of normalized enrichment score (NES), from which we could observe that ALOX12 expression was tightly associated with tumor development, progression, metastasis, and immune-related pathways such as positive regulation of GTPase activity, small GTPase-mediated signal transduction, NOTCH signaling pathway, regulation of GTPase activity, ECM receptor interaction, and inositol phosphate metabolism pathways. Here, ALOX12 is linked to neoplasm.