These include the cancer testis antigens (e.g., New York Esophageal Squamous Cell Car- cinoma-1 (NY-ESO-1)), differentiation antigens (e.g., Melanoma antigen family A-3 (MAGE-A3)), overexpressed oncogenes (e.g., Wilms’ Tumor antigen 1 (WT1)), tumor suppressor genes (e.g., Tumor Protein P53(TP53)); and TAAs that are organ-specific antigens that are transiently expressed. This evidence concerns the gene TP53 and cancer.