Furthermore, enforced expression of Lnc90386 aggravated MG-induced apoptosis (Figure 9D), increased the expression of pro-apoptotic genes including FAS, Casp3, Casp8 and Casp9, and decreased the expression of the anti-apoptotic gene BCL-2 (Figures 9E, F). The gene discussed is CASP3; the disease is myasthenia gravis.