After 24 hours of infection, BTN2A transcriptional expression for both isoforms (BTN2A1 and BTN2A2) was significantly increased after C. burnetii NM1 and Guiana infection (BTN2A1 p=0.0170 and p=0.0021, respectively; and BTN2A2 p=0.0054 and p=0.0463, respectively) compared to uninfected cells and without significant modulation compared to the heat-inactivated form (Figure 1C). Here, BTN2A1 is linked to infection.