For example, in BP, the MEturquoise module was enriched in chromosome segregation, nuclear division, nuclear chromosome segregation, DNA replication, etc. In CC, MEturquoise module was enriched in chromosome region, spindle, condensed chromosome, etc. In MF, MEturquoise module was enriched in ATPase activity, tubulin binding, microtubule binding, DNA replication origin binding, etc. Whereas MEblue module was mainly enriched in tumor microenvironment such as vasculogenesis and may have some relationship in tumor metastasis (Figures 3D, E). This evidence concerns the gene DNAH8 and neoplasm.