Similarly, KEGG pathway enrichment analysis exhibited that in the MEturquoise module, genes were related to cell cycle, DNA Replication, p53 signaling pathway, cell senescence, mismatch repair, and base excision repair; whereas in the MEblue module, genes were enriched in cell adhesion molecules and vascular smooth muscle contraction, which may play an important role in tumor metastasis (Figures 3F, G). This evidence concerns the gene TP53 and neoplasm.