While the CHA2DS2-VASc score uses clinical variables, the more-recent ABC (Age, Biomarkers, Clinical history)-stroke score incorporates age and clinical history of previous stroke/transient ischemic attack with two cardiac biomarkers: high sensitivity cardiac troponin T (hs-cTnT) and the pro-B-type natriuretic peptide N-terminal fragment (NT-proBNP) (8–11). The gene discussed is NPPB; the disease is transient ischemic attack.