It has been shown that the coding region of the paired cassette gene, chromosome 2q13, is fused to the coding region of the peroxisome proliferator-activated receptor γ, 3q13, to form a new gene, PAX8-PPARγ, which is characteristically expressed in follicular thyroid cancer (FTC) and also in other thyroid tumor tissue types; its positive expression rate varies among different ethnic and geographical populations. The gene discussed is PPARG; the disease is thyroid tumor.