Since our previous experiments confirmed that PAX8-PPARγ was specifically expressed in solid tumor tissues of thyroid cancer and had an impact on its malignant biological behavior both in vivo and ex vivo, this would potentially provide a new molecular tumor marker for thyroid cancer and provide the necessary experimental basis for the next quantitative assessment of PAX8-PPARγ aggregation in thyroid cancer in vivo by molecular imaging methods. The gene discussed is PAX8; the disease is thyroid cancer.