PAX8 and thyroid cancer: In addition, after receiving different concentrations of the PAX8-PPARγ antisense oligonucleotide treatment (Figures 2(c)–2(e)), an increase in apoptosis of thyroid cancer cells was also observed with the decrease of PAX8-PPARγ protein expression, suggesting a positive role of PAX8-PPARγ in the survival and proliferation of thyroid cancer cells.