Since our previous experiments confirmed that PAX8-PPARγ was expressed in solid tumor tissues of thyroid cancer and had an impact on its malignant biological behavior both in vivo and ex vivo, this would potentially provide a new molecular tumor marker for thyroid cancer and provide the necessary experimental basis for the next quantitative assessment of PAX8-PPARγ aggregation in thyroid cancer by molecular imaging methods in vivo. This evidence concerns the gene PAX8 and neoplasm.