BECN1 and non-small cell lung carcinoma: In tumor xenograft studies, tumors of NSCLC cells expressing BECN1-EEE exhibit lower basal autophagy and higher levels of apoptosis but, surprisingly, grew much faster than cells expressing the BECN1-wild-type (BECN1-WT) or the BECN1-AAA mutant (where phosphotyrosine sites were substituted with the non-phosphorylatable alanine, A).