After the transfer of hsa_circ_0001610 by M2-sEVs to endometrial cancer cells, cyclin B1 expression is upregulated through miRNA-139-5p, which affects the G2/M phase of the cell cycle, when the cells are the most sensitive to radiation, reduces the radiosensitivity of endometrial cancer cells, and affects prognosis (Gu et al., 2021) (see Table 2). Here, CCNB1 is linked to endometrial cancer.