The results of echocardiography showed that LVEF (16.02 ± 6.8% vs. 35.14 ± 5.0%, P < 0.05) (Figures 2(a) and 2(b)) and LVFS (10.62 ± 4.09% vs. 18.01 ± 1.16%, P < 0.05) (Figures 2(a) and 2(b)) in the PCSK9−/− ischemia group were significantly higher than that in the WT ischemia group. The gene discussed is PCSK9; the disease is ischemia.