Of these 14 mutated genes in HCC, compared with mutant genes in PHL in this study (ACTB, IRF4, CD79B, DNM2, CCT6B, ASXL3, RUNX1, PTPN6, PRDM1, PTPRD, FLT3, ERBB3, and TP53), we found no other same mutant gene between the PHL and HCC groups except for the TP53 gene. The gene discussed is RUNX1; the disease is hepatocellular carcinoma.