BRD2 and breast cancer: ROC curve analysis for peak 2012 m/z comparing the breast cancer stages I-III to NAT shows significant ROC AUC values when comparing NAT vs. Stage I (AUC 0.84; p-value: 0.0192), NAT vs. Stage II (AUC 0.82; p-value: 0.005) and NAT vs. Stage III (AUC 0.84; p-value: 0.009) (Figure 5C).