AIFM2 and central nervous system cancer: demonstrated that TGF−β1 increases FSP1 expression in human bronchial epithelial cells (62), as TGF−β1 is an important cytokine that can be secreted by glioma or/and immune cell (17, 63, 64), and it means that FSP1 could be a nexus between glioma or/and immune cell ferroptosis.