Moreover, the prevalence of stroke significantly decreased with increasing quartiles of serum DHEA in women (24.8% in quartile 1, 21.3% in quartile 2, 18.2% in quartile 3, and 9.9% in quartile 4; p = 0.003) and DHEAS in men (24.4% in quartile 1, 21.9% in quartile 2, 13.3% in quartile 3, and 14.2% in quartile 4; p = 0.011). This evidence concerns the gene SULT2A1 and stroke disorder.