In particular, IL-1β and IL-6 are well recognized to contribute to oncogenesis and their expression is abundantly found in GBM cell lines and tissues (Lu et al., 2007; Yeung et al., 2012; Liu et al., 2021), IL-6, in particular, is associated with poorer prognosis (Hori et al., 2019). The gene discussed is IL1B; the disease is glioblastoma.