Treg is a kind of immunosuppressive cells that participates in the pathogenesis of IBD in the intestinal microenvironment (Galvez, 2014), which controls intestinal inflammatory response mainly through the secretion of anti-inflammatory cytokines such as IL-10 and TGF-β (Mayne and Williams, 2013). Here, TGFB1 is linked to inflammatory bowel disease.