However, except for acute promyelocytic leukemia (APL) and core-binding factor (CBF) AML, prognosis remains dismal with conventional chemotherapy (3 + 7 regimen: 3 days of daunorubicin + 7 days of cytarabine), which might have reached the limit for treating AML [4-7]. The gene discussed is CEBPZ; the disease is acute myeloid leukemia.