Shi et al. 54 developed a unique liposome FA-L@MD@CAT to encapsulate catalase (CAT), a photosensitizer (MBDP), and adriamycin to catalyze the overexpression of H2O2 in tumors and increase tumor oxygenation, thereby reversing the immunosuppressive TME (Figure 6A). This evidence concerns the gene CAT and neoplasm.