IL17A and ischemia: In response to ischemia, the placenta releases a mixture of factors, including proinflammatory cytokines [i.e., tumor necrosis factor‐alpha (TNF‐α) and interleukin 17 (IL‐17)], anti‐angiogenic factors [i.e., fms‐like tyrosine kinase 1 (sFlt‐1) and soluble endoglin], and reactive oxygen species (ROS) into the maternal circulation causing widespread endothelial dysfunction that results in enhanced peripheral vasoconstriction and hypertension (Aouache et al., 2018; Goulopoulou & Davidge, 2015; Sargent et al., 2006; Wang et al., 2009).