VSIR and extranodal nasal NK/T cell lymphoma: In NK/T cell lymphoma, the count of CD8+ TILs increases with the high expression of VISTA and higher with the co-expression of VISTA and PD-L1, and the single marker high expression of VISTA is correlated with the increase of Foxp3+ TILs, but the immune regulation mechanisms are still unknown, besides, high expression of VISTA predicts poor prognosis, thus, maybe the overexpression of VISTA promotes the accumulation of immune cells but inhibits their function?