CD274 and neoplasm: In testicular germ cell tumors, the low counts of tumor-associated immune cells expressed with PD-L1 and VISTA may be related to stage I patients’ relapse but not for stage II and stage III, the high platelet-to-lymphocyte ratio and low counts of VISTA express tumor-associated immune cells which are the biomarkers to predict worse prognosis of testicular germ cell tumors in patients (HR = 15.56, P = 0.001 and HR = 4.1, P = 0.006, respectively) [97].