NFKB1 and cardiovascular disorder: The results of the present study suggests that there are differences in the incidence of MACCEs among patients who are at high risk of cardiovascular diseases with different NFKB1 genotypes, with the HR of MACCEs for DD genotype being 2.294 times higher than that for II or DD genotype, suggesting that NFKB1 gene mutation are a high-risk factor for the prognosis of cardiovascular diseases.