Compared with those without NAFLD, patients with NAFLD, regardless of the presence or absence of significant fibrosis, were more likely to be younger, centrally obese, and more insulin resistant (as reflected by a higher HOMA-IR score) and also had greater diastolic blood pressure and higher serum ALT and triglyceride concentrations. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.