Bezafibrate, an agonist for peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α), has been shown to boost antitumor immunity by upregulating mitochondrial OXPHOS and inhibiting apoptosis in an MC38-bearing mouse tumor model treated with PD-1 blockade [135]. Here, PPARGC1A is linked to neoplasm.