The number of discrete areas of NeuN staining over 101 μm2 was reduced in DCM compared to control tissue (Fig. 1e), but the number of discrete areas of NeuN staining over 23.3 μm2 was comparable (Fig. 1d).Furthermore, the total area of NeuN staining was reduced in DCM (Fig. 1h), and the mean area of NeuN staining per cell (when analysing discrete regions over 23.3 μm2) was reduced (Fig. 1i). The gene discussed is RBFOX3; the disease is familial dilated cardiomyopathy.