For NCC, isorhamnetin-O-rutinoside-O-arabinoside, the compound that reduced the expression for the greatest extent was also the compound that mostly decreased ALT and AST, besides ononin was the top compound responsible for the restoration of albumin synthetic function which indicates a very close association between cirrhosis degree and the NCC renal expression. This evidence concerns the gene SLC12A3 and Cirrhosis.