Induction of cirrhosis resulted in 3.3 and 2.8 folds increase in Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels, respectively and 2.4 fold decrease in serum albumin level, Fig. 5A. The high and/or intermediate doses of three of the tested Astragalus extracts (As-rt D3, As-ar D2, As-ar D3, At-ar D2 and At-ar D3) were able to return ALT to its basal levels. This evidence concerns the gene ALB and Cirrhosis.