CD4 and cancer: Overall, we noted more CD8+ T clones were shared between tumor lesions with P1 (7.64% of the total intratumoral CD8+ T clones), then nearest non-cancer tissues (7.14% of the total intratumoral CD8+ T clones), whereas tumor-infiltrating CD4+ T cells shared more clones with distal normal tissues (only 1.26% of the total intratumoral CD4+ T clones).