INS and type 2 diabetes mellitus: Even relatively modest exercise can stimulate immediate and persistent insulin sensitivity the next day in adults at risk of T2DM.40 The men in our study completed on average 410 min of MVPA/week while average MVPA/week in the women was 240 min, which may account for the additional effect of PA on postprandial glucose uptake, with skeletal muscle being the major site of uptake.