Given the association between obstructive sleep apnea and Alzheimer's disease, the observed increase in iron content may reflect deposition of amyloid‐β and/or tau protein – especially in the medial parieto‐occipital lobe (André et al., 2020) – as iron is abundantly present in amyloid plaques and neurofibrillary tangles (Smith, Harris, Sayre, & Perry, 1997; van Duijn et al., 2017). This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.