Notably, a total of 10 hub genes namely, MRPL16, MRPL22, MRPS11, RPL26L1, ESR1, JUN, UBE2I, MRPL17, RPL37A and GTF2H3 were identified from the DEGs of PCOS and EC endometrial tissues. Here, GTF2H3 is linked to polycystic ovary syndrome.