Although transcript levels for ISGs (e.g. Stat1) were not altered, the expression of various genes coding for inflammatory factors (Il1b, Il6) was enhanced in obese NASH hamsters, whereas the expression of genes coding for anti-inflammatory factors (Il10) was diminished (Figure 1e, the fold inductions, relative to mock-infected animals of the same diet, are depicted). Here, IL10 is linked to metabolic dysfunction-associated steatohepatitis.