Accordingly, the pulmonary virus-induced expression of genes related to interferons (IFNs) and interferon-stimulated genes (ISGs) (such as Stat1, Mx1 and Cxcl10) was the same in lean hamsters and obese NASH hamsters (Supplementary Figure S1d). This evidence concerns the gene STING1 and metabolic dysfunction-associated steatohepatitis.