This correction of critical metabolic pathways on gene expression level was accompanied by a significant decrease in histological liver inflammation, and suppression of FFD‐stimulated cytokine and chemokine proteins KC/CXCL1, MCP‐1/CCL2, and MIP‐2/CXCL2 and their pathways. This evidence concerns the gene CXCL2 and digestive system neoplasm.