Consistently, the LLC and EL4 inoculated Klf1K74R/K74R mice exhibited a reduction in tumor growth compared to Klf1+/+ mice (0.17 ± 0.05 g vs 0.50 ± 0.11 g, p < 0.01; 460 ± 65 cm3 vs 156.56 ± 46.35 cm3, p < 0.05 and 0.33 ± 0.16 g vs 1.03 ± 0.66 g. The gene discussed is KLF1; the disease is neoplasm.