11PLAG1 encodes for a zinc finger transcription factor that regulates the transcription of many genes, including insulin‐like growth factor 2 (IGF2)48. PLAG1 is frequently upregulated by translocations in several benign mesenchymal tumors, including pleomorphic adenomas and lipoblastomas49, 50. HMGA2 is widely used as a biomarker for leiomyomas of the HMGA2‐subtype, but our results indicate that PLAG1 expression could serve as a biomarker for the whole HMGA‐subtype. This evidence concerns the gene IGF2 and neoplasm.