In this study, we performed 3′RNA‐sequencing to explore the expression pattern of 111 leiomyomas previously classified as negative for driver alterations in MED12, HMGA2, and FH by Sanger sequencing (MED12) and immunohistochemistry (HMGA2 and FH).16, 17, 18, 19, 20. Here, HMGA2 is linked to leiomyoma.