This replicates and contributes to other studies that have shown that higher BDNF levels and increased Aβ ratio are indicative of a lower risk for dementia (van Oijen et al., 2006; Weinstein et al., 2014; Chouraki et al., 2015; Lopez et al., 2019; Miranda et al., 2019). The gene discussed is BDNF; the disease is dementia.