Dilated cardiomyopathy (DCM) and heart failure (HF) 6–8 weeks after KO. Mitochondria have preserved cristae; however, they were larger and more elongated. In this study, mitochondrial autophagy and mitochondrial stress were assessed using p62, LC3, LONP2, AFG3L2, and Hsp60 Western blots. Here, AFG3L2 is linked to familial dilated cardiomyopathy.