The numbers of autophagic vacuoles were quantified in rat HF and hypertension models with truncated titin and exposure to Ang II and SIM (Hsieh et al., 2019; Zhou et al., 2019) and qualitatively evaluated in Ang II model in combination with cathepsin S KO (Pan et al., 2012) (Table 3). This evidence concerns the gene AGT and hypertensive disorder.