ATF6 and Parkinson disease: It has been determined that UPR parameters, including GRP78, IRE1, ATF6, PERK, eIF2α, and CHOP, are increased in patients with AD (Garcia-Gonzalez et al., 2018), PD (Gerakis and Hetz, 2018), ALS (Prell et al., 2019), and prion diseases (Lindholm et al., 2017).