Previous reports have shown that SARS-CoV-2 peptide stimulation significantly induces IFNγ production by CD4+ T cells from unexposed individuals (Braun et al., 2020; Grifoni et al., 2020; Le Bert et al., 2020; Mateus et al., 2020; Meckiff et al., 2020; Sekine et al., 2020; Weiskopf et al., 2020) and that the Th1 response is associated with an effective resolution of infection and symptoms in COVID-19 (Chen et al., 2020; Neidleman et al., 2020). The gene discussed is CD4; the disease is infection.