In AD, for example, mitophagy stimulation restores memory loss via PINK-1, PDR-1 (Parkinson’s disease-related-1; parkin), or DCT-1 (DAF-16/FOXO-controlled germline-tumor-tumor-affecting-1)-dependent pathways (Fang et al., 2019a). This evidence concerns the gene PINK1 and Alzheimer disease.