CD8 TRM cells from old mice have been shown to drive lung fibrosis following influenza, SARS-CoV-2 and chikungunya infections, potentially via TGFβ, likely delaying recovering of lung function and promoting conditions for secondary infection and other age associated lung disorders (Uhrlaub et al., 2016; Goplen et al., 2020; Goplen et al., 2021; Shenoy and Mizgerd, 2021). Here, CD8A is linked to influenza.